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How Hemp is Transforming the Mental Health Space—Clinical Trials and Research Studies

How Hemp is Transforming the Mental Health Space—Clinical Trials and Research Studies

Hemp is a variety of the cannabis sativa plant, used for industrial purposes in a myriad of different products. Industrial hemp, like bamboo, is one of the fastest-growing plants in the world. With loosening global regulations and legalization under the 2018 Farm Bill, researchers everywhere have jumped on the chance to utilize hemp’s advantages to research and treat several physical disorders—such as nerve pain, chemotherapy-induced illness, epilepsy, and muscle spasticity. Now taking a more legitimate title as medicinal cannabis, it has been reported to help not only the body but the mind, too.

Affective Disorders

With increased scientific research, hemp has been used to treat different behavior conditions that disrupt mood regulation. Treatment for affective disorders (and all disorders) involves consumption, inhalation, or topical absorption of the plant and can be taken in the form of oil, gummies, serums, and more.

Anxiety

In a 2017 clinical study, the endocannabinoid system was discovered to moderate anxiety and mood, with supporting data finding cannabinoids and other substances stimulating the prefrontal cortex, amygdaloid complex, bed nucleus of stria terminalis, and hippocampus in the brain. Cannabis derivations like hemp target these areas to relieve anxiety and serve as an antidepressant mediated through its serotonergic properties (5-HT1A receptor activation and THC’s CB1 receptor agonism). 

Though there’s limited research to prove that hemp completely cures Generalized Anxiety Disorder and Social Anxiety Disorder, it assists in alleviating anxiety levels in the brain. Using Hemp Pharamicist’s concentrated Ananda or CBDMD gummies for anxiety, roll-ons, or CBD oil can help soothe stress for a clear mind.

Post-traumatic Stress Disorder (PTSD)

The whole cannabis plant has been observed to relieve PTSD symptoms, specifically in veterans. The prefrontal cortex, amygdala, and hippocampus release fear in the brain, which, when impaired by medicinal cannabis, improves responses by triggering stimuli.  

One 2014 survey of 170 patients at a medical cannabis dispensary in California found that those with high PTSD scores preferred cannabidiol for sleep improvement and coping. Along with its psychological benefits, hemp-derived CBD can be used in CBD oil to soften and brighten the skin with stress-relieving properties.

Depression

Depression is rising in America, with over 20% of adults in 2019-2020 experiencing the blues. Phytocannabinoids and terpenes drawn from the hemp plant directly affect the endocannabinoid system to act as an antidepressant. However, it illustrates that heavy cannabis users could increase susceptibility to depression, so we recommend using either a low THC dosage of cannabis or CBD gummies, which have 0.3% or less of THC. On a positive note, in a cross-sectional survey of 1429 medical cannabis users, over 50% use cannabis to treat depression. 

Insomnia

Many studies and reports suggest the positive effects of hemp on sleep, including this case study of 72 adults experiencing poor sleep. Sleep scores strengthened within the first month in 48 patients (66.7%) but shifted over time. Overall, CBD was well-tolerated in all but three patients. CBD oil for sleep or hemp night cream can apply this effect with natural, full-spectrum extracts.

Psychotic Disorders

These mental illnesses can impact everyday life with cognitive impairment, social problems, and stressful mental patterns. Hemp can be a shield to keep unhealthy thoughts at bay and reduce distractions.

Schizophrenia

There has been a consistent link between hemp and cannabis in schizophrenia treatment. Though heavy cannabis use can hinder the disorder with enhanced psychosis, healthy consumption of non-THC counterparts like CBD provides an opposite effect to THC inebriation. A double-blind parallel-group trial involving 88 schizophrenia patients gave them either oral CBD (1000 mg/day) or a placebo to replace their antipsychotic medication for six weeks— revealing that the CBD party had lower levels of positive psychotic symptoms on the Positive and Negative Syndrome Scale (PANSS) and a higher chance of being considered clinically improved.

Attention Deficit Hyperactivity Disorder (ADHD)

Adults with ADHD favored cannabis as their choice of self-medication in a 2016 study. The observed outcome of cannabis users reported higher cognitive performance and improved activity levels. Hyperactivity/impulsivity can also be alleviated, with hemp terpenes and cannabinoids performing a calming effect on the brain.  

Overstimulation in the brain can also pair with other mental illnesses like depression and anxiety.  Our medical-grade hemp specialists recommend a full-spectrum CBDa formula to take with your daily dose of vitamins as a focus booster.  Full-spectrum cannabidiolic acid softgels break down in the body with 3x higher Cmax (peak serum concentration) levels than CBD when taken alone.

Conclusion

At The Hemp Pharmacist, we are enthusiasts of a hemp-explored future. We believe that embracing the full potential of the cannabis plant can reveal holistic alternatives to pharmaceutical dependence and even ween people off some conventional drugs. More clinical research is needed to prove hemp’s full, comprehensive effects on physical and mental health. With your increased interest in full-spectrum, natural hemp, we can evolve into a healthier community.

Take a mental health day every day with our pharmaceutical-grade hemp products—experience hemp’s benefits with CBD oil, Koi CBD gummies, and more. For extra information or dosage assistance, reach out to our professionals here.

**The information provided in this blog is for educational purposes only and is not intended as medical advice. While we strive to provide accurate and up-to-date information about CBD and its potential uses, we are not healthcare professionals. The statements made regarding CBD products have not been evaluated by the Food and Drug Administration.**

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CBD Awareness Month 2023: Celebrate With cbdMD this January

CBD Awareness Month 2023: Celebrate With cbdMD this January

It’s no secret that CBD has greened out the world (and all its people) with love for the hemp plant; we even invented a month for it. Every year, our medical professionals at cbdMD have dubbed January the official CBD Awareness Month— where we embrace all of the life-changing benefits full-spectrum CBD encompasses for physical wellness, mental health, and much more.

CBD—What’s So Special About It?

Since the 2018 Farm Bill passed, CBD has exploded in popularity and leveraged in many forms, like CBD oil tinctures, edibles for pain relief, immunity gummies, anxiety roll-ons, and pet products (the list goes on) to treat virtually anything. The recognition is due to CBD’s striking similarities with its counterpart, cannabis. The main difference is that CBD does not contain tetrahydrocannabinol (THC), the leading chemical responsible for getting you high.  

Because it does not get you high, CBD has been incorporated into many people’s daily lives and routines, even attracting the attention of public figures and celebrities who voice its benefits.

The History of National CBD Month

But great things don’t come without backlash. The close connection between CBD and cannabis—which was only just federally legalized for adult consumption in 2018— has garnered a negative outlook from the media. People began to reject CBD on the mere basis that it spawns from a previously classified Schedule I drug, causing people to question the legitimacy of its positive impact. That’s why cbdMD has made every January a CBD holiday to fight the negative stigma and counterfeit products surrounding it.

Because cannabidiol oil (CBD) contains less than 0.3% THC, which is legal under the 2018 Farm Bill, it became the perfect loophole for consumers and researchers to explore its effects. In 2019, the Journal of the American Medical Association (JAMA) found that CBD was the fourth most Google-searched health topic in April. This study revealed to the world that CBD is in high demand, and people want it.

Our partners at cbdMD founded National CBD Month in 2020 to celebrate the normalization of CBD and its increased integration into our society. We are on a daily mission to ensure everyone is educated on the wonders of CBD and make our full-spectrum CBD formula (made from all of the good parts of the hemp plant) available to all. With our recent 2022 win with the Medical Marijuana and Cannabidiol Research Expansion Act, we’ve streamlined our CBD skincare products, gummies, oil tinctures, and more from our ISO-certified labs to millions of homes nationwide. 

CBD Awareness Month Timeline

CBD has effectively taken the world by storm over the past decade. Let’s break down some of the key milestones that have caused the 2020 launch of our beloved holiday below.

2014 – The Fight for Legalization Begins

The 2014 Agriculture Act makes hemp-derived CBD legal in the U.S. Utah becomes the first state to pass legislation for low-THC high-CBD legalization, followed by ten more states by the end of the year.

2015 – Medical Breakthroughs 

A surge of professional research (around 49 clinical studies) finds that CBD can help manage a multitude of problems. See what some of those are here.

2017 – WADA Approves

The World Anti-Doping Agency permits hemp-drawn compound CBD cannabidiol use. The Californication of commercially sold industrial hemp through Senate Bill 566 enacts as a result.

2018 – The Farm Bill

CBD extracted from hemp (not marijuana) and has less than 0.3% THC becomes federally legal, removing hemp from the Controlled Substances Act (CSA).

How Can I Celebrate?

Spend CBD Awareness Month your way with endless activities that include the mind-relaxing remedy. Incorporate cannabidiol into the new year by using this month to reflect, experiment, and relax. This January is the perfect opportunity to share CBD with a family member or friend to explore your health together. Here are a few ideas from cbdMD that you can try with a partner or solo:

  • Enhance your skincare routine.  Our CBD Botanicals Facial Exfoliant, Body Butter, and Body Oil use a holistic, full-spectrum formula to rehydrate and rejuvenate damaged skin.
  • Detox the mind and body.  Choosing CBD and healthy foods over processed foods and over-the-counter medications triggers your body to flush out years’ worth of toxins. Our vitamin-packed Immunity Gummies are available in three strengths to restore mental, cardiac, and digestive health.
  • Relax and recover. It’s essential to give yourself a break, especially after a day of strenuous work or exercise. Replenish tense muscles with a topical Cream or use an Anxiety Roll On to soothe stress through a mind-to-muscle connection.

Now that you know the ins and outs of CBD, why not make self-care your New Year’s Resolution? Put your health first by exploring CBD with the Hemp Pharmacist, your reputable medical provider. Need a mindful healing guide?  Call The Hemp Pharmacist for dosage assistance and hemp-related questions. Happy CBD Awareness Month!

**The information provided in this blog is for educational purposes only and is not intended as medical advice. While we strive to provide accurate and up-to-date information about CBD and its potential uses, we are not healthcare professionals. The statements made regarding CBD products have not been evaluated by the Food and Drug Administration.**

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CBD vs CBN: Key Differences, Similarities, and Potential Uses

CBD vs CBN: Key Differences, Similarities, and Potential Uses

The popularity of hemp-derived compounds for the relief of a variety of physical symptoms is increasing exponentially. Recent changes in the laws regulating the use of cannabis products in consumer products removed hemp products containing less than 0.3 percent THC (the psychoactive compound in marijuana responsible for the “high”) from the legal definition of marijuana as per the Controlled Substances Act. 

These changes have fueled more thorough and focused research into the viability of hemp-based compounds as having clinical potential. There is an ever-increasing body of knowledge becoming available, and clinical trials are revealing how cannabis-based compounds can be used to develop medications to treat a growing number of symptoms.

When exploring the world of hemp-based products, there are a couple of key compounds that get most of the coverage. Two of the most talked-about compounds are CBD (cannabidiol) and CBN (cannabinol). While the names may be difficult to distinguish from one another, they originate from the same place, and they both interact with the body’s endocannabinoid system. Their effects can often be similar, yet with a couple of key differences.

What is CBD (cannabidiol)? 

Of approximately 150 identified compounds found in the cannabis plant, CBD or cannabidiol is second to THC in abundance. Due to its proportional presence, it is one of the better known, and one of the most studied compounds. As opposed to the psychoactive effects of THC, CBD has a counterbalancing regulatory effect. 

Of the developed hemp-derived compounds, CBD is considered to provide the most abundant potential for wellness benefits. People have been seeking CBD products for pain relief more frequently than ever, and CBD has been shown to be effective in stress reduction for dogs. There are many cannabis-derived products with CBD as their primary ingredient, and can be introduced in a variety of ways:

  • Smoking or vaping- CBD for pain and stress relief
  • Orally- oils, edibles, and beverages for pain relief and stress management
  • Topically- includes creams and lotions for relief from pain and itching and CBD oil for arthritis as cosmetics and skincare applications.

What is CBN (cannabinol)?

One of the lesser-known phytocannabinoids, CBN or cannabinol, is produced by the degradation of the THC molecule through the process of decarboxylation (prolonged exposure to heat and oxygen). While up to 75% or more of the potency of THC may be lost during this process, CBN is not considered to be entire without some psychoactive potential. 

Unlike CBD which has no psychoactive effect, CBN can potentially produce psychoactive reactions in higher dosages, so caution is required. CBN is gaining recognition for its potential in enhancing the “Entourage Effect” of the application of full-spectrum cannabinoids. Among the compounds being studied, CBD is considered to be particularly effective in creating a relaxing, sleep-enhancing effect. 

CBD and CBN products are available in isolates (which contain CBD or CBN only), broad-spectrum (containing a number of cannabis compounds, but no THC), or full spectrum (which contains all available compounds, but by law may contain less than 0.3% THC).  

As with all nonprescription cannabis-derived products, they are not regulated by the FDA. Some products may contain inaccurate or misleading labeling or content descriptions. It is best that you consult a professional CBD pharmacist like the professionals at The Hemp Pharmacist at 757-577-1024. They are available to make recommendations specific to your needs. 

Note- For informational purposes only. Please consult your physician before beginning or discontinuing any medication. CBD or CBN should not be used with any medication containing a “grapefruit warning”.  Commercial cannabis compounds may, by law, contain no more than 0.3 % of THC. While this is not enough THC to create a psychoactive effect, it may still be detectable in some tests. If you are prohibited from using any product containing THC or any hemp-derived products, CBD/CBN treatments may not be an option.

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CBD Dosage: How Much CBD Should You Take?

CBD Dosage: How Much CBD Should You Take

The popularity of hemp-derived products as an alternative or adjunct treatment for a variety of disorders is growing exponentially. A peer-reviewed study published in 2017 found CBD to be a relatively safe and effective treatment of certain symptoms associated with various problems. Research is unlocking the possibilities of hemp-based compounds as a potential treatment for additional disorders.

What is CBD? How Does it Work? 

CBD, or Cannabidiol, is one of over 90 compounds to date identified as phytocannabinoids. Cannabinoids interact with receptors in the endocannabinoid system in the bodies of mammals. The endocannabinoid system is responsible for the regulation of communication between cells in the body and influences appetite, inflammation, mood, and memory. While CBD doesn’t specifically bind to either CB1 or CB2 (primary cannabinoid receptors), it is found to affect serotonin receptors in certain concentrations. It is noted that CBD oil for pain relief is among the most popular usages. 

How to use CBD? 

CBD is available in a growing number of applications and delivery methods, such as full-spectrum CBD oil tinctures, CBD oil roll-ons, topical CBD creams and oils, gummies, vapes, and sublingual tinctures. New products are entering the market. Consult your CBD pharmacy professional for additional information about what products may be best for you.

As with any supplement or substance, it is always advisable to begin with a low dosage and work up to find the optimum dosage for your body type and specific symptoms. CBD has been found to be safe for humans in moderate amounts. Up to 1,500 mg per day is generally well tolerated by most people. It is considered low-risk and often recommended as a supplemental treatment. Side effects are usually minor, including dry mouth, dizziness, fatigue, and abdominal upset.

CBD is commonly available as: 

  • Isolates: This contains CBD and no other compounds.
  • Broad-spectrum CBD: This includes other compounds found in the cannabis plant but contains no THC.
  • Full-spectrum CBD: This contains trace amounts of THC, the psychoactive compound in marijuana. Federal law prohibits more than 0.3% THC in any commercially available CBD or hemp-derived product. Full-spectrum CBD is the most highly recommended type due to the “entourage effect,” the compounds work in concert to provide maximum results where the whole is greater than the sum of its parts.

CBD Dosage Recommendations 

Finding the correct effective dosage will vary by body weight, lifestyle, and exposure to other substances. Alcohol, THC, opioids, and amphetamines compromise the endocannabinoid system and may require a period of abstinence or higher dosages of CBD. Caffeine, nicotine, NSAIDs, and the cortisol resulting from chronic exposure to stress can affect the dosage needed. 

A good rule of thumb for beginners is to consult your physician before beginning any treatment regimen. As for dosage- begin slowly and increase as needed. Your results may vary. 

Representative recommended beginning dosing amounts of CBD:

Weight

Mild Effect

Moderate Effect

Strong Effect

Under 140 lbs

> 12 mg

13-15 mg

15-18 mg

140-250 lbs

> 20 mg

20-23 mg

24-28 mg

Over 250 lbs

> 24 mg

25-30 mg

31-46 mg

Representative recommended beginning dosing amounts of CBD:One caveat- Buyer Beware. The FDA does not currently regulate CBD compounds, so the concentration and efficacy of products may vary by vendor. Trusting a professional CBD pharmacist who supplies tested and certified CBD products is always the best policy.  

Call us today to get CBD products that will suit your needs.

Note- For informational purposes only. Please consult your physician before beginning or discontinuing any medication. CBD should not be used with any medication containing a “grapefruit warning.”  Commercial cannabis compounds may, by law, have no more than 0.3 % of THC. While this is not enough THC to create a psychoactive effect, it may still be detectable in some tests. If you are prohibited from using any product containing THC or any hemp-derived products, CBD treatments may not be an option.

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